Mutation Information
Mutation Site
|
G84D |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
Vif |
Literature Information
PubMed PMID
|
24418540
|
Published Year
|
2014 |
Journal
|
Virology |
Title
|
Defining HIV-1 Vif residues that interact with CBFβ by site-directed mutagenesis. |
Author
|
Matsui Y,Shindo K,Nagata K,Io K,Tada K,Iwai F,Kobayashi M,Kadowaki N,Harris RS,Takaori-Kondo A |
Evidence
|
Although we transfected with the same amount of plasmid DNA, expression levels of E88A, W38A, D14/R15AA, Y40A, Y69A and G84D were comparable to wild-type Vif, but those of W89A, E88/W89A and W21A mutants were obviously impaired (Fig. S1, 2nd top panel).
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