|
Mutation Information
|
Mutation Site
|
G7521A |
|
Mutation Type
|
Nucleotide level |
|
Gene/Protein/Region Type
|
LCR |
|
Genotype/Subtype
|
HPV16 |
|
Viral Reference
|
K02718.1
|
|
Country
|
Argentina |
Literature Information
|
PubMed PMID
|
25735347
|
|
Disease
|
High grade squamous intraepithelial lesion;
Low grade squamous intraepithelial lesion
|
|
Published Year
|
2015 |
|
Journal
|
Asian Pacific journal of cancer prevention : APJCP |
|
Title
|
Mutation detection of E6 and LCR genes from HPV 16 associated with carcinogenesis. |
|
Author
|
Mosmann JP,Monetti MS,Frutos MC,Kiguen AX,Venezuela RF,Cuffini CG |
|
Evidence
|
The most frequent mutation in LCR sequences was G7521A, in 80% of the analyzed samples; it affects the binding site of a transcription factor that could contribute to carcinogenesis.
|
|
|
HPV Mutation Detail Information