Mutation Information
Mutation Site
|
G73S |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
PR |
Country
|
USA |
Literature Information
PubMed PMID
|
18645523
|
Disease
|
HIV infection/AIDS
|
Published Year
|
2008 |
Journal
|
Journal of acquired immune deficiency syndromes (1999) |
Title
|
In vitro characterization of multidrug-resistant HIV-1 isolates from a recently infected patient associated with dual tropism and rapid disease progression. |
Author
|
Mohri H,Markowitz M |
Evidence
|
Phenotype tests including replication capacity were performed on all plasma-derived viruses in patients MDR-1-4 (Table 3). Among MDR-1 isolates, the drug resistance-associated amino acid changes in protease, i.e., L10I, L33F, M46I, I54M, L63F, I66F, A71V, G73S, I84V and L90M were shared with all biological clones.
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