HPV Mutation Detail Information

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Mutation Information
Mutation Site G6719A
Mutation Type Nucleotide level
Gene/Protein/Region Type L1
Genotype/Subtype HPV16
Country Tunis
Literature Information
PubMed PMID 30583341
Disease High grade squamous intraepithelial lesion; Low grade squamous intraepithelial lesion; Cervical carcinoma
Published Year 2018
Journal Asian Pacific journal of cancer prevention : APJCP
Title Phylogeny and Classification of Human Papillomavirus (HPV)16 and HPV18 Variants Based on E6 and L1 genes in Tunisian Women with Cervical Lesions
Author Jendoubi-Ferchichi M,Satouri L,Ghoul F,Malek-Mellouli M,Derbel AM,Makni MK,Reziga H,Baba A,Zili M,Segondy M,Khelifa R
Evidence Indeed, within the 392-nt sequence in ORF E6 (nt 228 to 620), HPV16 strains showed a T350G nt change which is specific to the European German lineage A2 [27] and lead to a L83V substitution, whereas in ORF L1, one isolate showed the (G6719A) substitution, only found in the African sub-lineage B1.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation