HBV Mutation Detail Information

> G660C Search Result


Mutation Information
Mutation Site G660C
Mutation Type Nucleotide level
Gene/Protein/Region Type S
Nucleotide_Mutation R169P
Genotype/Subtype A
Immune Escape Y
Literature Information
PubMed PMID 20881037
Published Year 2010
Journal Journal of virology
Title Impairment of hepatitis B virus virion secretion by single-amino-acid substitutions in the small envelope protein and rescue by a novel glycosylation site.
Author Ito K,Qin Y,Guarnieri M,Garcia T,Kwei K,Mizokami M,Zhang J,Li J,Wands JR,Tong S
Evidence In this regard, the I110M, G119E, M133T, and R169P substitutions in the envelope proteins are caused by the T484G, G510A, T552C, and G660C point mutations in the viral genome, respectively (Fig. ​(Fig.1A),1A), with the T484G mutation further inducing an S466A substitution in the DNA polymerase. 

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation