|
Mutation Information
|
Mutation Site
|
G63S |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
E7 |
|
Genotype/Subtype
|
HPV58 |
Literature Information
|
PubMed PMID
|
28794033
|
|
Published Year
|
2017 |
|
Journal
|
Journal of virology |
|
Title
|
Ancient Evolution and Dispersion of Human Papillomavirus 58 Variants. |
|
Author
|
Chen Z,Ho WCS,Boon SS,Law PTY,Chan MCW,DeSalle R,Burk RD,Chan PKS |
|
Evidence
|
The distribution and oncogenic potential of HPV58 variants appear to be heterogeneous, since the E7 T20I/G63S variant is more prevalent in East Asia and confers a 7- to 9-fold-higher risk of cervical precancer and cancer.
|
|
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HPV Mutation Detail Information