|
Mutation Information
|
Mutation Site
|
G63S |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
E7 |
|
Amino acid_Mutation
|
G760A |
|
Genotype/Subtype
|
HPV58 |
|
Viral Reference
|
NC_001443.1
|
|
Country
|
China |
Literature Information
|
PubMed PMID
|
12189229
|
|
Disease
|
Cervical carcinoma;
Cervical intraepithelial neoplasia
|
|
Published Year
|
2002 |
|
Journal
|
Journal of the National Cancer Institute |
|
Title
|
Association of human papillomavirus type 58 variant with the risk of cervical cancer. |
|
Author
|
Chan PK,Lam CW,Cheung TH,Li WW,Lo KW,Chan MY,Cheung JL,Cheng AF |
|
Evidence
|
Among HPV58-positive women, the occurrence of E7 632C-->T (T20I) and E7 760G-->A (G63S) variants (T20I/G63S) showed a positive trend of association with the severity of neoplasia (P(trend)<.001, chi(2) test for trend).
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HPV Mutation Detail Information