Mutation Information
Mutation Site
|
G48V |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
PR |
Relevant Drug
|
darunavir (DRV) |
Literature Information
PubMed PMID
|
27992544
|
Published Year
|
2016 |
Journal
|
PloS one |
Title
|
Structural Studies of a Rationally Selected Multi-Drug Resistant HIV-1 Protease Reveal Synergistic Effect of Distal Mutations on Flap Dynamics. |
Author
|
Agniswamy J,Louis JM,Roche J,Harrison RW,Weber IT |
Evidence
|
The flaps of PRS17 harbor 3 mutations, M46L, G48V and I54V.
|
|
|