|
Mutation Information
|
Mutation Site
|
G44G |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
S |
|
Genotype/Subtype
|
D |
|
Viral Reference
|
AY090460;
AY090457;
AY090454;
AF405706;
AB064310;
AF160501;
AF223965;
AB036910;
X69798;
AB032431;
X75657;
X85254;
M32138;
X65259;
AB014381;
M12906;
X04615;
AB033554;
AF100309;
D00329;
AF090842;
X51970;
X02763 |
|
Country
|
Italy |
Literature Information
|
PubMed PMID
|
27486882
|
|
Disease
|
Occult HBV infection;
Hepatocellular carcinoma;
Liver cirrhosis
|
|
Published Year
|
2016 |
|
Journal
|
Oncotarget |
|
Title
|
Occult HBV infection in HCC and cirrhotic tissue of HBsAg-negative patients: a virological and clinical study. |
|
Author
|
Coppola N,Onorato L,Iodice V,Starace M,Minichini C,Farella N,Liorre G,Filippini P,Sagnelli E,de Stefano G |
|
Evidence
|
In this patient, the HCC tissue showed no mutation in the S region, AA substitutions L54P and G76A and AA deletions in positions 4, 8 and 17 in the pre-S1 region and AA substitution P41H in the pre-S2 region, whereas the non-HCC liver tissue showed the G44G/E and I92T AA substitutions in the S region, G91A and I255T AA substitutions in the pre-S1 region and AA substitutions G99E and I147T in the pre-S2 regions.
|
|
|
HBV Mutation Detail Information