|
Mutation Information
|
Mutation Site
|
G44E |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
S |
|
Relevant Drug
|
telbivudine (LDT) |
|
Country
|
China |
Literature Information
|
PubMed PMID
|
27583985
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2017 |
|
Journal
|
Antiviral therapy |
|
Title
|
Small surface antigen variants of HBV associated with responses to telbivudine treatment in chronic hepatitis B patients. |
|
Author
|
Dong H,Zhou B,Kang H,Jin W,Zhu Y,Shen Y,Sun J,Wang S,Zhao G,Hou J,He Y |
|
Evidence
|
RESULTS: Sequencing results revealed different dynamics of non-synonymous mutations, such as sL9P, sN40S, sG44E, sW172*, sW182* and sS187F, between patients with a complete virological response and those with a partial virological response.
|
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HBV Mutation Detail Information