HPV Mutation Detail Information

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Mutation Information

Mutation Site	G437A
Mutation Type	Nucleotide level
Gene/Protein/Region Type	E6
Genotype/Subtype	HPV18
Viral Reference	AY262282
Country	Costa Rica;Taiwan;Thailand;Rwanda;Burkina Faso;Zambia

Literature Information

PubMed PMID	23977318
Disease	HPV infection
Published Year	2013
Journal	PloS one
Title	Evolution and taxonomic classification of alphapapillomavirus 7 complete genomes: HPV18, HPV39, HPV45, HPV59, HPV68 and HPV70.
Author	Chen Z,Schiffman M,Herrero R,DeSalle R,Anastos K,Segondy M,Sahasrabuddhe VV,Gravitt PE,Hsing AW,Burk RD
Evidence	Lineage C variants could be distinguished by 23 SNPs throughout the complete genome (E6 - G437A; E1 - T1526C, A1636G; E2 – G3757C, C3790T; E5 – T3942C, T3963G; L2- T4423G, G4486A, A4513T, A4726G, G5191A, C5225A, G5351A; L1 – A5638G, G5764A, A5880G, T5942G, A6224T, T6536C, A6644C, A6845C; and URR- T7475G), while lineages A and B had 62 and 33 lineage specific nucleotide variations, respectively (Figure S1A and Figure S2).

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation