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Mutation Information
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Mutation Site
|
G431A |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
Env |
|
Viral Reference
|
K02013.1
|
Literature Information
|
PubMed PMID
|
17134507
|
|
Published Year
|
2006 |
|
Journal
|
Retrovirology |
|
Title
|
Second site escape of a T20-dependent HIV-1 variant by a single amino acid change in the CD4 binding region of the envelope glycoprotein. |
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Author
|
Baldwin CE,Berkhout B |
|
Evidence
|
However, when an alternative neutral amino acid (alanine which is the most analogous amino acid to the endogenous glycine;G431A) was introduced into the wild-type virus, replication and syncytia formation was re-established.
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HIV Mutation Detail Information