EBV Mutation Detail Information

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Mutation Information
Mutation Site G373D
Mutation Type Amino acid level
Gene/Protein/Region Type EBNA3A
Viral Reference NC007605.1
Country Guangzhou;China
Literature Information
PubMed PMID 30546078
Disease Extranodal natural killer T-cell lymphoma; Nasopharyngeal carcinoma; Gastric carcinoma
Published Year 2019
Journal Leukemia
Title Genomic and transcriptomic landscapes of Epstein-Barr virus in extranodal natural killer T-cell lymphoma.
Author Peng RJ,Han BW,Cai QQ,Zuo XY,Xia T,Chen JR,Feng LN,Lim JQ,Chen SW,Zeng MS,Guo YM,Li B,Xia XJ,Xia Y,Laurensia Y,Chia BKH,Huang HQ,Young KH,Lim ST,Ong CK,Zeng YX,Bei JX
Evidence Notably, 21 of these epitopes with significant enrichment in NKTCL samples were restricted to six EBV genes, including EBNA3A (G373D, F325L, I333K, L406P, S412R, H464R, M466R, T585I, and A588P), EBNA3B (A399S, V400L, V417L, K424T, Y662D, and K663E), EBNA3C (P916S), BARF1 (V29A), BCRF1 (V6M), and BNRF1 (G456R, S497G, and A1291T).

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation