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Mutation Information

Mutation Site	G310R
Mutation Type	Amino acid level
Gene/Protein/Region Type	Gp120

Literature Information

PubMed PMID	33883222
Published Year	2021
Journal	Journal of virology
Title	Species-specific valid ternary interactions of HIV-1 Env-gp120, CD4, and CCR5 as revealed by an adaptive single-amino acid substitution at the V3 loop tip.
Author	Koma T,Yokoyama M,Kotani O,Doi N,Nakanishi N,Okubo H,Adachi S,Adachi A,Sato H,Nomaguchi M
Evidence	Virological analyses showed that a G310R substitution at the tip of the gp120 V3 loop selectively abolished the viral replication ability in human cells, despite evoking enhancement of viral replication in macaque cells.

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Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation