Mutation Information
Mutation Site
|
G281W |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
L1 |
Genotype/Subtype
|
HPV16 |
Literature Information
PubMed PMID
|
28968823
|
Published Year
|
2017 |
Journal
|
The Journal of infectious diseases |
Title
|
Naturally Occurring Single Amino Acid Substitution in the L1 Major Capsid Protein of Human Papillomavirus Type 16: Alteration of Susceptibility to Antibody-Mediated Neutralization. |
Author
|
Ning T,Wolfe A,Nie J,Huang W,Chen XS,Wang Y |
Evidence
|
The 50% tissue culture infective doses of the other 8 mutant PsVs (G281W, S282P, N285H, S302L, C428W, K430Q, K430H, and K467R) were 1–3 orders of magnitude lower than those for the reference PsVs (Figure 1).
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