HPV Mutation Detail Information

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Mutation Information
Mutation Site G2249A
Mutation Type Nucleotide level
Gene/Protein/Region Type E1
Nucleotide_Mutation R462K
Genotype/Subtype HPV16
Viral Reference K02718.1
Country Greek
Literature Information
PubMed PMID 23881083
Disease Cervical carcinoma; Cervical intraepithelial neoplasia
Published Year 2014
Journal Archives of virology
Title Nucleotide polymorphisms of the human papillomavirus 16 E1 gene.
Author Tsakogiannis D,Darmis F,Gortsilas P,Ruether IG,Kyriakopoulou Z,Dimitriou TG,Amoutzias G,Markoulatos P
Evidence In addition sequence analysis of the E1 region revealed the nucleotide variations C2041T, G2220C, C2237G, G2249A, C2262T, C2287T and C2344T, from which the nucleotide variations C2041T, G2220C, C2237G, and G2249A induced the amino acid changes L393I, E425D, T458S, and R462K, while the C2262T, C2287T, and C2344T changes were silent nucleotide variations.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation