EBV Mutation Detail Information

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Mutation Information
Mutation Site G212S
Mutation Type Amino acid level
Gene/Protein/Region Type LMP1
Literature Information
PubMed PMID 32038504
Published Year 2019
Journal Frontiers in microbiology
Title Epstein-Barr Virus Latent Membrane Protein 1 Regulates Host B Cell MicroRNA-155 and Its Target FOXO3a via PI3K p110α Activation.
Author Hatton O,Smith MM,Alexander M,Mandell M,Sherman C,Stesney MW,Hui ST,Dohrn G,Medrano J,Ringwalt K,Harris-Arnold A,Maloney EM,Krams SM,Martinez OM
Evidence All of the LMP1 tumor variants, but not B95.8 LMP1, contain the same point mutations in their C-terminal domains, each within a specific CTAR: a glycine to serine mutation at amino acid 212 in CTAR1 and a serine to threonine mutation at amino acid 366 in CTAR2.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation