Mutation Information
Mutation Site
|
G212S |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
LMP1 |
Literature Information
PubMed PMID
|
32038504
|
Published Year
|
2019 |
Journal
|
Frontiers in microbiology |
Title
|
Epstein-Barr Virus Latent Membrane Protein 1 Regulates Host B Cell MicroRNA-155 and Its Target FOXO3a via PI3K p110α Activation. |
Author
|
Hatton O,Smith MM,Alexander M,Mandell M,Sherman C,Stesney MW,Hui ST,Dohrn G,Medrano J,Ringwalt K,Harris-Arnold A,Maloney EM,Krams SM,Martinez OM |
Evidence
|
All of the LMP1 tumor variants, but not B95.8 LMP1, contain the same point mutations in their C-terminal domains, each within a specific CTAR: a glycine to serine mutation at amino acid 212 in CTAR1 and a serine to threonine mutation at amino acid 366 in CTAR2.
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