Mutation Information
Mutation Site
|
G207A |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
Large T |
Literature Information
PubMed PMID
|
21454559
|
Published Year
|
2011 |
Journal
|
The Journal of biological chemistry |
Title
|
Merkel cell polyomavirus large T antigen disrupts lysosome clustering by translocating human Vam6p from the cytoplasm to the nucleus. |
Author
|
Liu X,Hein J,Richardson SC,Basse PH,Toptan T,Moore PS,Gjoerup OV,Chang Y |
Evidence
|
MCV LT alanine substitution mutants, GST.LT(1-258).R204A, T205A, Y206A, G207A, T208A, and W209A were generated using the QuikChange Lighting Site-directed Mutagenesis Kit (Agilent) using GST.
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