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Mutation Information
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Mutation Site
|
G2011C |
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Mutation Type
|
Nucleotide level |
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Gene/Protein/Region Type
|
C |
Literature Information
|
PubMed PMID
|
28088502
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2017 |
|
Journal
|
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases |
|
Title
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The nucleotide changes within HBV core promoter/precore during the first 12weeks of nucleos(t)ide treatment might be associated with a better virological response. |
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Author
|
Peng Y,Li Y,Hou J,Sun J,Su M,Li Y,Xiang K,Yan L,Zhuang H,Li T |
|
Evidence
|
The C1969T and G2011A/C were found to increase mostly from 9.6% (5/52) at baseline to 17.3% (9/52) at week 12 of treatment (P = 0.250) and from 3.8% (2/52) at baseline to (11.5%, 6/52) at week 12 of treatment (P = 0.141), respectively.
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HBV Mutation Detail Information