Mutation Information
Mutation Site
|
G2003W |
Mutation Type
|
Nucleotide level |
Gene/Protein/Region Type
|
C |
Viral Reference
|
GU434373.1;
GU434374.1 |
Country
|
China |
Literature Information
PubMed PMID
|
20699378
|
Disease
|
Hepatocellular carcinoma
|
Published Year
|
2010 |
Journal
|
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology |
Title
|
Comparison study on the complete sequence of hepatitis B virus identifies new mutations in core gene associated with hepatocellular carcinoma. |
Author
|
Zhu Y,Jin Y,Guo X,Bai X,Chen T,Wang J,Qian G,Groopman JD,Gu J,Li J,Tu H |
Evidence
|
The frequencies of mutation increased in HCC patients, from 3.9% (C2002T), 23.3% (A2159G), 22.3% (A2189C), and 1.0% (G2003W) in non-HCC patients to 9.7%, 37.9%, 48.5%, and 10.7% in HCC patients, respectively.
|
|
|