HIV Mutation Detail Information

> G190S Search Result

Mutation Information

Mutation Site	G190S
Mutation Type	Amino acid level
Gene/Protein/Region Type	RT
Relevant Drug	nevirapine (NPV)
Country	Thailand

Literature Information

PubMed PMID	22132100
Disease	HIV infection/AIDS
Published Year	2011
Journal	PloS one
Title	Resistance patterns selected by nevirapine vs. efavirenz in HIV-infected patients failing first-line antiretroviral treatment: a bayesian analysis.
Author	Ngo-Giang-Huong N,Jourdain G,Amzal B,Sang-a-gad P,Lertkoonalak R,Eiamsirikit N,Tansuphasawasdikul S,Buranawanitchakorn Y,Yutthakasemsunt N,Mekviwattanawong S,McIntosh K,Lallemant M,Program for HIV Prevention and Treatment (PHPT) study group.
Evidence	In the NVP-based treatment group, 100% had virus with one or more NNRTI mutations: Y181C/I was present in 56% (18% as the sole mutation), G190A/S in 30% (4%) and K103N in 28% (18%).

Contents
Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation