|
Mutation Information
|
Mutation Site
|
G190A |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Relevant Drug
|
nevirapine (NPV);efavirenz (EFV) |
|
Country
|
Kenyans |
Literature Information
|
PubMed PMID
|
31956856
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2020 |
|
Journal
|
EClinicalMedicine |
|
Title
|
Pre-treatment HIV-drug resistance associated with virologic outcome of first-line NNRTI-antiretroviral therapy: A cohort study in Kenya. |
|
Author
|
Beck IA,Levine M,McGrath CJ,Bii S,Milne RS,Kingoo JM,So I,Andersen N,Dross S,Coombs RW,Kiarie J,Chohan B,Sakr SR,Chung MH,Frenkel LM |
|
Evidence
|
Mutations K103N, Y181C, G190A, M184V and K65R were detected by an oligonucleotide ligation assay (OLA) and confirmed by Sanger and next-generation sequencing (NGS).
|
|
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HIV Mutation Detail Information