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Mutation Information
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Mutation Site
|
G190A |
|
Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
RT |
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Viral Reference
|
K03455.1
|
|
Relevant Drug
|
NNRTIs |
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Country
|
Sierra Leone |
Literature Information
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PubMed PMID
|
30989237
|
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Disease
|
HIV infection/AIDS
|
|
Published Year
|
2019 |
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Journal
|
The Journal of antimicrobial chemotherapy |
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Title
|
Prevalence of drug resistance mutations among ART-naive and -experienced HIV-infected patients in Sierra Leone. |
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Author
|
Yendewa GA,Sahr F,Lakoh S,Ruiz M,Patiño L,Tabernilla A,Deen GF,Sesay M,Salata RA,Poveda E |
|
Evidence
|
The most prevalent RT PDR mutations were as follows: K103N (n = 7, 14.3%), M184V (n = 4, 8.2%) and Y181C (n = 2, 4.1%). Other mutations observed with a frequency of 2.0% were as follows: for NRTIs, D67N (n = 1), K70R (n = 1) and K219E (n = 1);and for NNRTIs, V106AM (n = 1) and G190A (n = 1) (Figure 1).
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HIV Mutation Detail Information