HBV Mutation Detail Information

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Mutation Information

Mutation Site	G1899A
Mutation Type	Nucleotide level
Gene/Protein/Region Type	PreC

Literature Information

PubMed PMID	33364535
Published Year	2020
Journal	AIMS microbiology
Title	Mutations and methods of analysis of mutations in Hepatitis B virus.
Author	Rajput MK
Evidence	Reverse transcriptase acts as a primer of RNA-directed DNA synthesis by binding to the bulge of ε. Encapsidation and replication of HBV may also be impaired by mutations in the upper stem and loop of ε. Mutations at the precore codon 17 (G1899A) have been found alone [35],[36] or together with other precore mutations like G1862T transversion [15] or the 28-stop codon mutation could also lead to HBeAg seronegativity.

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Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation