HBV Mutation Detail Information

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Mutation Information
Mutation Site G1899A
Mutation Type Nucleotide level
Gene/Protein/Region Type PreC
Combined Mutation prec.G1899A+prec.G1896A
Country Germany
Literature Information
PubMed PMID 33055418
Disease HBV infection
Published Year 2020
Journal JCI insight
Title Quadruple mutation GCAC1809-1812TTCT acts as a biomarker in healthy European HBV carriers.
Author Peiffer KH,Spengler C,Basic M,Jiang B,Kuhnhenn L,Obermann W,Zahn T,Glitscher M,Loglio A,Facchetti F,Carra G,Kubesch A,Vermehren J,Knop V,Graf C,Dietz J,Finkelmeier F,Herrmann E,Trebicka J,Grünweller A,Zeuzem S,Sarrazin C,Lampertico P,Hildt E
Evidence The specificity of the blot was proven by using an additional genome containing the precore double mutation G1896A/G1899A, which was used as an additional HBeAg negative control, and by using an HBeAg positive WT genome as a positive control (Figure 3A).

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation