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Mutation Information
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Mutation Site
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G1899A |
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Mutation Type
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Nucleotide level |
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Gene/Protein/Region Type
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PreC |
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Country
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China |
Literature Information
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PubMed PMID
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29628773
|
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Disease
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Hepatocellular carcinoma
|
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Published Year
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2018 |
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Journal
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Cancer management and research |
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Title
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The mutation of hepatitis B virus and the prognosis of hepatocellular carcinoma after surgery: a pilot study. |
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Author
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Zhang Y,Huang J,Chen J,Yang K,Chen J,Xu L,Zhou Z,Chen M |
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Evidence
|
Both A1762T/G1764A mutation and Pre S deletion related to worse overall survival (OS, p=0.040 and p<0.001, respectively) and disease-free survival (DFS, p=0.040 and p<0.001, respectively), G1899A mutation related to worse OS (p=0.030), A1762T/G1764A mutation correlated with tumor size (r=0.204, p=0.019), G1899A mutation correlated with vascular invasion (r=0.332, p<0.001), and Pre S deletion correlated with alpha-fetoprotein (AFP; r=0.254, p=0.003) positively.
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HBV Mutation Detail Information