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Mutation Information
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Mutation Site
|
G1899A |
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Mutation Type
|
Nucleotide level |
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Gene/Protein/Region Type
|
PreC |
Literature Information
|
PubMed PMID
|
22675557
|
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Disease
|
Hepatocellular carcinoma
|
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Published Year
|
2012 |
|
Journal
|
PloS one |
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Title
|
Precore mutation of hepatitis B virus may contribute to hepatocellular carcinoma risk: evidence from an updated meta-analysis. |
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Author
|
Liao Y,Hu X,Chen J,Cai B,Tang J,Ying B,Wang H,Wang L |
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Evidence
|
Statistically significant correlations were observed in Precore mutation G1896A (OR = 1.46, 95% confidence interval [CI] = 1.15-1.85, POR = 0.002), G1899A (OR = 3.13, 95%CI = 2.38-4.13, POR<0.001) and Pre-S mutation especially Pre-S1 deletion (OR = 2.94, 95%CI = 2.22 to 3.89) and Pre-S2 deletion (OR = 3.02, 95%CI = 2.03 to 4.50).
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HBV Mutation Detail Information