HBV Mutation Detail Information

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Mutation Information

Mutation Site	G1899A
Mutation Type	Nucleotide level
Gene/Protein/Region Type	PreC
Genotype/Subtype	D

Literature Information

PubMed PMID	12823591
Clinical information	Yes
Disease	HBV infection
Published Year	2003
Journal	Journal of viral hepatitis
Title	YSDD: a novel mutation in HBV DNA polymerase confers clinical resistance to lamivudine.
Author	Bozdayi AM,Uzunalimoğlu O,Türkyilmaz AR,Aslan N,Sezgin O,Sahin T,Bozdayi G,Cinar K,Pai SB,Pai R,Bozkaya H,Karayalçin S,Yurdaydin C,Schinazi RF
Evidence	Sequencing of the precore and core promoter regions revealed a stop codon as a result of the G to A change at nucleotide 1896 and additional G to A change at nucleotide 1899 in the precore, and wild type sequences, in the core promoter region.

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation