Mutation Information
Mutation Site
|
G1897A |
Mutation Type
|
Nucleotide level |
Gene/Protein/Region Type
|
PreC |
Country
|
Argentina |
Literature Information
PubMed PMID
|
25822666
|
Disease
|
Acute exacerbation of chronic hepatitis B
|
Published Year
|
2015 |
Journal
|
PloS one |
Title
|
Hepatitis B virus genotype distribution and genotype-specific BCP/preCore substitutions in acute and chronic infections in Argentina. |
Author
|
González López Ledesma MM,Mojsiejczuk LN,Rodrigo B,Sevic I,Mammana L,Galdame O,Gadano A,Fainboim H,Campos R,Flichman D |
Evidence
|
In the preCore region, G1896A was the most common mutation (55.2%), whereas other mutations that prevent HBeAg synthesis, such as those affecting the preCore initiation codon (nt 1814–1816), mutations (C1817T, G1897A), insertions and deletions that create a premature stop codon, were observed in a lower frequency (33.3%).
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