Mutation Information
Mutation Site
|
G1896G |
Mutation Type
|
Nucleotide level |
Gene/Protein/Region Type
|
PreC |
Genotype/Subtype
|
E |
Country
|
Abidjan; Côte d'Ivoire |
Literature Information
PubMed PMID
|
29660214
|
Disease
|
HBV-HIV coinfection
|
Published Year
|
2018 |
Journal
|
Journal of viral hepatitis |
Title
|
Precore G1896A mutation is associated with reduced rates of HBsAg seroclearance in treated HIV hepatitis B virus co-infected patients from Western Africa. |
Author
|
Boyd A,Moh R,Maylin S,Abdou Chekaraou M,Mahjoub N,Gabillard D,Anglaret X,Eholié SP,Delaugerre C,Danel C,Zoulim F,Lacombe K,ANRS 12240 VarBVA study. |
Evidence
|
Roughly two- thirds of patients (59.3%) harboured the G1896A or mixed G1896G/A pc mutation and almost one- quarter of patients harboured the A1762T (21.2%) or G1764A (24.7%) BCP mutations.
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