HBV Mutation Detail Information

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Mutation Information
Mutation Site G1896A
Mutation Type Nucleotide level
Gene/Protein/Region Type PreC
Country Greek
Literature Information
PubMed PMID 9751010
Disease Chronic hepatitis B
Published Year 1998
Journal Journal of viral hepatitis
Title Incidence and clinical significance of hepatitis B virus precore gene translation initiation mutations in e antigen-negative patients.
Author Laras A,Koskinas J,Avgidis K,Hadziyannis SJ
Evidence These data show that a significant proportion of HBeAg-negative patients who already harbour the 1896 stop codon mutation may subsequently develop precore translation initiation mutations, which appear to be associated with enhanced HBV replication and severe liver disease.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation