Mutation Information
Mutation Site
|
G1896A |
Mutation Type
|
Nucleotide level |
Gene/Protein/Region Type
|
PreC |
Genotype/Subtype
|
B;C |
Country
|
china |
Literature Information
PubMed PMID
|
33296295
|
Published Year
|
2021 |
Journal
|
Emerging microbes & infections |
Title
|
Specific determination of hepatitis B e antigen by antibodies targeting precore unique epitope facilitates clinical diagnosis and drug evaluation against hepatitis B virus infection. |
Author
|
Wang SJ,Chen ZM,Wei M,Liu JQ,Li ZL,Shi TS,Nian S,Fu R,Wu YT,Zhang YL,Wang YB,Zhang TY,Zhang J,Xiong JH,Tong SP,Ge SX,Yuan Q,Xia NS |
Evidence
|
In contrast to widely used commercial assays, the NTR-HBeAg completely eliminated the cross-reactivity with secreted HBcAg from precore mutant (G1896A) virus in either cell culture or patient sera.
|
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