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Mutation Information
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Mutation Site
|
G1896A |
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Mutation Type
|
Nucleotide level |
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Gene/Protein/Region Type
|
PreC |
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Combined Mutation
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prec.G1899A+prec.G1896A |
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Country
|
Germany |
Literature Information
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PubMed PMID
|
33055418
|
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Disease
|
HBV infection
|
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Published Year
|
2020 |
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Journal
|
JCI insight |
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Title
|
Quadruple mutation GCAC1809-1812TTCT acts as a biomarker in healthy European HBV carriers. |
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Author
|
Peiffer KH,Spengler C,Basic M,Jiang B,Kuhnhenn L,Obermann W,Zahn T,Glitscher M,Loglio A,Facchetti F,Carra G,Kubesch A,Vermehren J,Knop V,Graf C,Dietz J,Finkelmeier F,Herrmann E,Trebicka J,Grünweller A,Zeuzem S,Sarrazin C,Lampertico P,Hildt E |
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Evidence
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The specificity of the blot was proven by using an additional genome containing the precore double mutation G1896A/G1899A, which was used as an additional HBeAg negative control, and by using an HBeAg positive WT genome as a positive control (Figure 3A).
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HBV Mutation Detail Information