HBV Mutation Detail Information

> G1896A Search Result

Mutation Information

Mutation Site	G1896A
Mutation Type	Nucleotide level
Gene/Protein/Region Type	PreC

Literature Information

PubMed PMID	30404796
Published Year	2019
Journal	Journal of virology
Title	Hepatitis B e Antigen Inhibits NF-κB Activity by Interrupting K63-Linked Ubiquitination of NEMO.
Author	Wang Y,Cui L,Yang G,Zhan J,Guo L,Chen Y,Fan C,Liu D,Guo D
Evidence	It is reported that the hepatitis B e antigen (HBeAg) can interfere with NF-kappaB activity, which then leads to high viral loads, while HBV with the G1896A mutation remains infectious without the production of HBeAg but can induce more severe proinflammatory response and liver damage.

Contents
Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation