HBV Mutation Detail Information

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Mutation Information
Mutation Site G1896A
Mutation Type Nucleotide level
Gene/Protein/Region Type PreC
Genotype/Subtype C;D
Country China
Literature Information
PubMed PMID 30043328
Disease HBV infection
Published Year 2018
Journal Hepatology international
Title Clinical implication and viral mutation in basal core promoter/pre-core of hepatitis B virus C/D recombinant.
Author Li H,She Q,Liu Y,Ding Y,Shi S,Li J,Wu H,Wang Z
Evidence The distribution of C2 and C/D did not differ by disease status or liver function. Significantly higher levels of HBV DNA (6.7 +- 1.6 vs. 5.9 +- 1.5, p = 0.014), HBeAg (263.5 vs. 20.0, p = 0.013) and A1762T/G1764A double-mutations (81.0 vs. 61.8%, p = 0.018), but a lower frequency of G1896A stop mutation (33.6 vs. 76.5%, p < 0.001) was observed in patients with the C/D recombinant than in patients with genotype C2.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation