Mutation Information
Mutation Site
|
G1896A |
Mutation Type
|
Nucleotide level |
Gene/Protein/Region Type
|
PreC |
Genotype/Subtype
|
C |
Country
|
Japan |
Literature Information
PubMed PMID
|
25593470
|
Disease
|
HBV infection
|
Published Year
|
2015 |
Journal
|
World journal of gastroenterology |
Title
|
Mutations of pre-core and basal core promoter before and after hepatitis B e antigen seroconversion. |
Author
|
Kamijo N,Matsumoto A,Umemura T,Shibata S,Ichikawa Y,Kimura T,Komatsu M,Tanaka E |
Evidence
|
METHODS: The proportion of pre-core (G1896A) and basal core promoter (A1762T and G1764A) mutant viruses and serum levels of hepatitis B virus (HBV) DNA, hepatitis B surface antigen (HBsAg), and HB core-related antigen were analyzed inChronic hepatitis Bpatients before and after HBeAg seroconversion (n = 25), in those who were persistently HBeAg positive (n = 18), and in those who were persistently anti-HBe positive (n = 43).
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