Mutation Information
Mutation Site
|
G1896A |
Mutation Type
|
Nucleotide level |
Gene/Protein/Region Type
|
PreC |
Genotype/Subtype
|
C |
Country
|
China |
Literature Information
PubMed PMID
|
24006435
|
Disease
|
Chronic hepatitis B
|
Published Year
|
2013 |
Journal
|
Journal of virology |
Title
|
HLA-DP polymorphisms affect the outcomes of chronic hepatitis B virus infections, possibly through interacting with viral mutations. |
Author
|
Zhang Q,Yin J,Zhang Y,Deng Y,Ji X,Du Y,Pu R,Han Y,Zhao J,Han X,Zhang H,Cao G |
Evidence
|
HLA-DP polymorphisms promoting HBV clearance were associated with a lower prevalence of mutations increasing HCC risk (C1653T, T1674C/G, A1846T, G1896A and pre-S2 mutations and pre-S deletion in genotype C) and a higher prevalence of mutations decreasing HCC risk (G1652A, T1673C, T1674C, G1719T, G1730C, and G1799C in genotype B and A1727T in genotype C).
|
|
|