HBV Mutation Detail Information

> G1896A Search Result

Mutation Information

Mutation Site	G1896A
Mutation Type	Nucleotide level
Gene/Protein/Region Type	PreC
Relevant Drug	entecavir (ETV)
Country	Japan

Literature Information

PubMed PMID	22523569
Disease	Chronic hepatitis B
Published Year	2012
Journal	PloS one
Title	Dynamics of hepatitis B virus quasispecies in association with nucleos(t)ide analogue treatment determined by ultra-deep sequencing.
Author	Nishijima N,Marusawa H,Ueda Y,Takahashi K,Nasu A,Osaki Y,Kou T,Yazumi S,Fujiwara T,Tsuchiya S,Shimizu K,Uemoto S,Chiba T
Evidence	Four of eight (50%) chronic therapy-naive HBeAg-negative patients showed a relatively low prevalence of the G1896A pre-core (pre-C) mutant in the liver tissues, suggesting that other mutations were involved in their HBeAg seroconversion.

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation