|
Mutation Information
|
Mutation Site
|
G1896A |
|
Mutation Type
|
Nucleotide level |
|
Gene/Protein/Region Type
|
PreC |
|
Genotype/Subtype
|
D |
|
Relevant Drug
|
lamivudine (LAM) |
|
Country
|
Iran |
Literature Information
|
PubMed PMID
|
22246826
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2012 |
|
Journal
|
Journal of medical virology |
|
Title
|
Characterization of hepatitis B virus genome variability in Iranian patients with chronic infection, a nationwide study. |
|
Author
|
Mohebbi SR,Amini-Bavil-Olyaee S,Zali N,Damavand B,Azimzadeh P,Derakhshan F,Sabahi F,Zali MR |
|
Evidence
|
PC and BCP mutations were observed in older patients, especially in those with chronic liver disease. Sixty-seven patients (82.7%) were HBeAg negative, and the prevalence of precore mutant isolates (G1896A) was higher in this group than in HBeAg-positive patients.
|
|
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HBV Mutation Detail Information