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Mutation Information
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Mutation Site
|
G1896A |
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Mutation Type
|
Nucleotide level |
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Gene/Protein/Region Type
|
PreC |
Literature Information
|
PubMed PMID
|
21860069
|
|
Published Year
|
2011 |
|
Journal
|
Antiviral chemistry & chemotherapy |
|
Title
|
The YMDD and rtA194T mutations result in decreased replication capacity in wild-type HBV as well as in HBV with precore and basal core promoter mutations. |
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Author
|
Zhu Y,Curtis M,Borroto-Esoda K |
|
Evidence
|
Therefore, merely stabilizing the T1858:G1896 base pairing in the ε stem-loop structure did not lead to the increased HBV DNA replication as seen with the G1896A PC mutation.
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HBV Mutation Detail Information