Mutation Information
Mutation Site
|
G1896A |
Mutation Type
|
Nucleotide level |
Gene/Protein/Region Type
|
PreC |
Country
|
Spain |
Literature Information
PubMed PMID
|
21311107
|
Disease
|
Chronic hepatitis B
|
Published Year
|
2011 |
Journal
|
Antiviral therapy |
Title
|
HBV core region variability: effect of antiviral treatments on main epitopic regions. |
Author
|
Homs M,Jardi R,Buti M,Schaper M,Tabernero D,Fernandez-Fernandez P,Quer J,Esteban R,Rodriguez-Frias F |
Evidence
|
Regarding the presence (mutant) or absence (wild type) of the main precore mutation G1896A, a signifi-cant difference in Av12 was observed in the B74–84 region (mean [range] 0.43 [0–2] wild type versus 1.35 [0–6] mutant; P=0.02) and a trend approaching sig-nificance was observed in the Th50–69 region (mean [range] 0.7 [0–6] wild type versus 1.13 [0–4] mutant; P=0.07).
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