|
Mutation Information
|
Mutation Site
|
G1896A |
|
Mutation Type
|
Nucleotide level |
|
Gene/Protein/Region Type
|
PreC |
|
Genotype/Subtype
|
B |
|
Country
|
Taiwan;China |
Literature Information
|
PubMed PMID
|
21168854
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2011 |
|
Journal
|
The Journal of pediatrics |
|
Title
|
Human interleukin-10 genotypes are associated with different precore/core gene mutation patterns in children with chronic hepatitis B virus infection. |
|
Author
|
Wu JF,Ni YH,Lin YT,Lee TJ,Hsu SH,Chen HL,Tsuei DJ,Hsu HY,Chang MH |
|
Evidence
|
HBV precore/core gene mutation increased significantly more in the inflammatory phase than in the tolerance phase (G1896A, 76.2% versus 4.8%; C1913A, 33.3% versus 0%; C2189A, 28.6% versus 4.8%; G2304A, 52.4% versus 14.3%) in study group (n = 21) but not the control group (n = 9).
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HBV Mutation Detail Information