HBV Mutation Detail Information

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Mutation Information
Mutation Site G1896A
Mutation Type Nucleotide level
Gene/Protein/Region Type PreC
Genotype/Subtype B
Country Japan
Literature Information
PubMed PMID 19850315
Disease Fulminant hepatitis B
Published Year 2009
Journal Virology
Title Enhanced intracellular retention of a hepatitis B virus strain associated with fulminant hepatitis.
Author Inoue J,Ueno Y,Nagasaki F,Wakui Y,Kondo Y,Fukushima K,Niitsuma H,Shimosegawa T
Evidence The pBFH2 construct with A1762T/G1764A, G1862T, and G1896A showed the largest amount of core particle-associated intracellular HBV DNA, but no significant increase of extracellular HBV DNA in comparison with the wild construct, suggesting that these mutations might work together for retention of the replicative intermediates in the cells.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation