Mutation Information
Mutation Site
|
G1896A |
Mutation Type
|
Nucleotide level |
Gene/Protein/Region Type
|
PreC |
Combined Mutation
|
prec.G1896A+c promoter.G1764A+c promoter.A1762T |
Genotype/Subtype
|
B;C |
Country
|
Vietnam |
Literature Information
PubMed PMID
|
17203204
|
Disease
|
Hepatocellular carcinoma;
Liver cirrhosis;
Chronic hepatitis B
|
Published Year
|
2007 |
Journal
|
International journal of molecular medicine |
Title
|
Genotype and variations in core promoter and pre-core regions are related to progression of disease in HBV-infected patients from Northern Vietnam. |
Author
|
Truong BX,Seo Y,Yano Y,Ho PT,Phuong TM,Long DV,Son NT,Long NC,Kato H,Hayashi Y,Trach NK,Kasuga M |
Evidence
|
The median age was matched between genotype B and C (38.2 vs. 42.9 years). The rates of HBeAg seroconversion and G1896A for genotype B were significantly higher than those for genotype C (P<0.05).
|
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