|
Mutation Information
|
Mutation Site
|
G1896A |
|
Mutation Type
|
Nucleotide level |
|
Gene/Protein/Region Type
|
PreC |
|
Genotype/Subtype
|
D |
|
Country
|
Australia |
Literature Information
|
PubMed PMID
|
17187404
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2007 |
|
Journal
|
Hepatology (Baltimore, Md.) |
|
Title
|
Regulation of Toll-like receptor-2 expression in chronic hepatitis B by the precore protein. |
|
Author
|
Visvanathan K,Skinner NA,Thompson AJ,Riordan SM,Sozzi V,Edwards R,Rodgers S,Kurtovic J,Chang J,Lewin S,Desmond P,Locarnini S |
|
Evidence
|
These results were confirmed in vitro using hepatic cell line transduced with recombinant HBV baculovirus expressing wild-type HBV (HBeAg-positive), precore stop codon (G1896A) mutant HBV (HBeAg-negative).
|
|
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HBV Mutation Detail Information