Mutation Information
Mutation Site
|
G1896A |
Mutation Type
|
Nucleotide level |
Gene/Protein/Region Type
|
PreC |
Combined Mutation
|
prec.G1896A+bcp.G1764A+bcp.A1762T |
Genotype/Subtype
|
B;C |
Viral Reference
|
AF233236;
AY293309 |
Country
|
Taiwan(China) |
Literature Information
PubMed PMID
|
16618410
|
Disease
|
Chronic hepatitis B;
Liver cirrhosis;
Hepatocellular carcinoma
|
Published Year
|
2006 |
Journal
|
Gastroenterology |
Title
|
High prevalence and mapping of pre-S deletion in hepatitis B virus carriers with progressive liver diseases. |
Author
|
Chen BF,Liu CJ,Jow GM,Chen PJ,Kao JH,Chen DS |
Evidence
|
The sequences of the pre-S region and the BCP (A1762T, G1764A) and PC (G1896A) mutations were determined in 46 HBV chronic carriers (CC) and 106 age-matched carriers with different stages of liver diseases, including 38 chronic hepatitis (CH), 18 cirrhosis (LC), and 50 hepatocellular carcinoma (HCC).
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