Mutation Information
Mutation Site
|
G1896A |
Mutation Type
|
Nucleotide level |
Gene/Protein/Region Type
|
PreC |
Nucleotide_Mutation
|
W28* |
Literature Information
PubMed PMID
|
16549970
|
Disease
|
HBV-HIV coinfection
|
Published Year
|
2006 |
Journal
|
AIDS (London, England) |
Title
|
Characteristics of drug resistant HBV in an international collaborative study of HIV-HBV-infected individuals on extended lamivudine therapy. |
Author
|
Matthews GV,Bartholomeusz A,Locarnini S,Ayres A,Sasaduesz J,Seaberg E,Cooper DA,Lewin S,Dore GJ,Thio CL |
Evidence
|
Five patients had pre-core mutations, with the classic mutation G1896A (pcW28stop, also known as the pre-core translational stop codon mutation) found in three patients, all of whom were genotype D and two of whom were HBeAg negative.
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