HBV Mutation Detail Information

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Mutation Information

Mutation Site	G1896A
Mutation Type	Nucleotide level
Gene/Protein/Region Type	PreC
Nucleotide_Mutation	W28*
Genotype/Subtype	D

Literature Information

PubMed PMID	15328117
Disease	Chronic hepatitis B
Published Year	2004
Journal	Antimicrobial agents and chemotherapy
Title	Clinical emergence of entecavir-resistant hepatitis B virus requires additional substitutions in virus already resistant to Lamivudine.
Author	Tenney DJ,Levine SM,Rose RE,Walsh AW,Weinheimer SP,Discotto L,Plym M,Pokornowski K,Yu CF,Angus P,Ayres A,Bartholomeusz A,Sievert W,Thompson G,Warner N,Locarnini S,Colonno RJ
Evidence	Patient B is a 55-year-old male who developed HBV disease recurrence following liver transplantation and who was HBV e antigen negative due to infection with precore-negative HBV (G1896A mutation resulting in a stop codon substitution for the codon corresponding to tryptophan at residue 28).

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation