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HBV Mutation Detail Information

> G1896A Search Result


Mutation Information
Mutation Site G1896A
Mutation Type Nucleotide level
Gene/Protein/Region Type PreC
Literature Information
PubMed PMID 12033768
Disease Chronic hepatitis B
Published Year 2002
Journal Virology
Title In vivo suppression of precore mRNA synthesis is associated with mutations in the hepatitis B virus core promoter.
Author Laras A,Koskinas J,Hadziyannis SJ
Evidence Precore mRNA synthesis was suppressed by the A1762T/G1764A mutation regardless of the presence of the precore stop codon mutation G1896A, suggesting that in addition to downregulating an immunomodulatory protein this double basic core promoter mutation may also confer a replication advantage to the virus.
Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation