HBV Mutation Detail Information

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Mutation Information

Mutation Site	G1862T
Mutation Type	Nucleotide level
Gene/Protein/Region Type	PreC
Genotype/Subtype	B
Country	Japan

Literature Information

PubMed PMID	19850315
Disease	Fulminant hepatitis B
Published Year	2009
Journal	Virology
Title	Enhanced intracellular retention of a hepatitis B virus strain associated with fulminant hepatitis.
Author	Inoue J,Ueno Y,Nagasaki F,Wakui Y,Kondo Y,Fukushima K,Niitsuma H,Shimosegawa T
Evidence	The pBFH2 construct with A1762T/G1764A, G1862T, and G1896A showed the largest amount of core particle-associated intracellular HBV DNA, but no significant increase of extracellular HBV DNA in comparison with the wild construct, suggesting that these mutations might work together for retention of the replicative intermediates in the cells.

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Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation